?男性和女性患者的感染、炎症和性功能
男性和女性患者的感染、炎症和性功能
——第五届国际性医学咨询会议 (ICSM 2024) 的建议
Infection, inflammation, and sexual function in male and female patients—recommendations from the Fifth International Consultation on Sexual Medicine (ICSM 2024)
——《性医学评论》2025年第13卷第3期——
【摘要】引言：男性和女性的性功能障碍是一个重要的临床问题；感染和炎症可导致社会、医学和心理问题，对全球的性健康和生殖健康产生深远影响。目的：我们旨在识别由感染和炎症引起的男性和女性性功能障碍，并提出有效的干预措施，这些措施已于2024年6月在西班牙马德里举行的第五届国际性医学咨询会议（ICSM）上得到评估。方法：我们在MEDLINE、Embase和Cochrane临床对照试验中心注册库（CENTRAL）中检索已发表的同行评审期刊文章，并在ClinicalTrials.gov和世界卫生组织（WHO）国际临床试验注册平台中检索前瞻性试验。本研究汇集了来自6个国家的10位专家在完成文献综述后达成的共识，并根据这些共识，列出了一系列强度等级的建议。本文件已提交给公开论坛进行同行评审和讨论，并根据第五届国际性传播疾病大会（ICSM）主席的建议进行了修订。结果：感染，尤其是性传播感染 (STI)，无论性取向和性别如何，都会严重影响个人和伴侣的性健康和生殖健康。同样，非传染性慢性疾病 (NCD) 通过炎症这一常见致病机制，可直接损害性交、生育和享受性生活的能力。结论：本专家共识建议优先考虑早期发现、综合治疗方法和预防措施，以减轻感染和炎症对患者和伴侣性健康的影响。这些见解为改善患者预后和提高全球对感染、炎症和性功能障碍之间相互关联性的认识奠定了基础。
【关键词】性功能障碍、慢性炎症、非传染性慢性疾病感染、性传播疾病 (STD)、慢性盆腔痛——新冠病毒病
[Abstract] Introduction: Sexual dysfunction in men and women is an important clinical issue; infection and inflammation can cause social, medical, and psychological problems that have a profound impact on sexual and reproductive health worldwide. Objectives: We set out to identify sexual dysfunctions in men and women that arise from infection and inflammation and propose meaningful interventions, as evaluated by the Fifth International Consultation on Sexual Medicine (ICSM) held in June 2024 in Madrid (Spain). Methods: We searched MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials (CENTRAL) for published peer-reviewed journal articles and ClinicalTrials.gov and the World Health Organization's (WHO’s) International Clinical Trials Registry Platform for prospective trials. This manuscript represents the opinions of 10 experts from 6 countries developed in a consensus process after completing the literature review, which produced a list of recommendations graded as weak or strong. This document was presented for peer review and debate in a public forum, and revisions were made based on the recommendations of chairpersons of the 5th ICSM. Results: Infections, and in particular sexually transmitted infections (STIs), dramatically affect the sexual and reproductive health of individuals and couples, irrespective of sexual orientation and gender. Similarly, non-communicable chronic diseases (NCDs), through the common pathogenetic mechanism of inflammation, can directly impair the ability to copulate, reproduce, and enjoy sexual life. Conclusions: This expert consensus recommends prioritizing early detection, comprehensive treatment approaches, and preventive measures to mitigate the effects of infection and inflammation on sexual health, both for the patient and the couple. These insights provide a foundation for improving patient outcomes and fostering global awareness of the interconnections between infection, inflammation, and sexual dysfunction.
[Key words] sexual dysfunction, chronic inflammation, NCD infection, STD, chronic pelvic pain—COVID-19
论文原文：Fernando Facio, Elena Colonnello, Laith Alzweri, et al (2025). Infection, inflammation, and sexual function in male and female patients—recommendations from the Fifth International Consultation on Sexual Medicine (ICSM 2024). Sexual Medicine Reviews, Volume 13, Issue 3, Pages 301–317. July 2025.
https://doi.org/10.1093/sxmrev/qeaf021
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